Neuronal Thermosensitivity

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Ionic channels and conductance-based models for hypothalamic neuronal thermosensitivity.

Thermoregulatory responses are partially controlled by the preoptic area and anterior hypothalamus (PO/AH), which contains a mixed population of temperature-sensitive and insensitive neurons. Immunohistochemical procedures identified the extent of various ionic channels in rat PO/AH neurons. These included pacemaker current channels [i.e., hyperpolarization-activated cyclic nucleotide-gated cha...

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Ion channel proteins in neuronal temperature transduction: from inferences to testable theories of deep-body thermosensitivity.

Ion channel proteins in neuronal temperature transduction: from inferences to testable theories of deep-body thermosensitivity.

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Mechano- and thermosensitivity of injured muscle afferents.

Injury of limb nerves leading to neuropathic pain mostly affects deep somatic nerves including muscle nerves. Here, we investigated the functional properties of injured afferent fibers innervating the lateral gastrocnemius-soleus muscle 4-13 h [time period (TP) I] and 4-7 days (TP II) after nerve crush in anesthetized rats using neurophysiological recordings from either the sciatic nerve (165 A...

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Spinal cord thermosensitivity: An afferent phenomenon?

We review the evidence for thermoregulatory temperature sensors in the mammalian spinal cord and reach the following conclusions. 1) Spinal cord temperature contributes physiologically to temperature regulation. 2) Parallel anterolateral ascending pathways transmit signals from spinal cooling and spinal warming: they overlap with the respective axon pathways of the dorsal horn neurons that are ...

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CALL FOR PAPERS Physiology and Pharmacology of Temperature Regulation Ionic channels and conductance-based models for hypothalamic neuronal thermosensitivity

Wechselberger, Martin, Chadwick L. Wright, Georgia A. Bishop, and Jack A. Boulant. Ionic channels and conductance-based models for hypothalamic neuronal thermosensitivity. Am J Physiol Regul Integr Comp Physiol 291: R518–R529, 2006. First published May 11, 2006; doi:10.1152/ajpregu.00039.2006.—Thermoregulatory responses are partially controlled by the preoptic area and anterior hypothalamus (PO...

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ژورنال

عنوان ژورنال: Science

سال: 1971

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.172.3990.1360